megatomi.com Can Be Fun For Anyone
megatomi.com Can Be Fun For Anyone
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Our new Apparent+ tissue clearing procedure is the one technique that delipidates samples with no change in morphology and with minimal influence on structural integrity.
Megatome is usually a vibrating microtome built to area a broad number of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With significant blade vibrating frequency and minimized blade deflection, Megatome allows high-throughput tissue sectioning with uniform surface profile, and also nominal tissue problems and data decline.
Antibodies might acquire weeks to diffuse by only a few millimeters of tissue, that has a steep labeling gradient from surface to Main.
Megatome is created for precision: the blade vibrates at a better frequency and bigger amplitude variety than other microtomes, and contains a distinctive deflection Management system.
SE uses a rotational electric discipline to disperse really electromobile molecules (like antibodies or surfactant micelles) during a porous sample without the need of harming electrically charged buildings inside the tissue. This permits two-four day clearing of intact organs,
Our preformulated EasyIndex Remedy raises and homogenize the refractive index of delipidated tissue samples, rendering them entirely transparent. This permits mild penetration into your sample and makes sure the acquisition of superior-resolution, in-emphasis graphic data.
Megatome is actually a novel microtome that permits for top-precision sectioning of a variety of tissue samples – from organoids, to arrays of animal organs, to intact human brain hemispheres – with minimal tissue damage and knowledge reduction.
It’s the perfect time to up grade your microtome to Megatome. With correct superior-frequency slicing for an unmatched array of sample dimensions and kinds – from organoids and tumors to expanded tissues, sample arrays, and intact primate organs – Megatome is optimized for numerous programs.
Totally delipidate full mouse brains or comparably sized samples in just one day with SmartBatch+, or in a single 7 days with our passive clearing kit.
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SHIELD avoids the variability of hydrogel embedding and the knowledge decline from PFA preservation, protecting specimens for numerous rounds of processing.
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Our novel Protect tissue preservation system sorts intramolecular bonds using polyfunctional, flexible epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.